All nations which have undergone a nutrition transition have experienced increased frequency and falling latency of chronic degenerative diseases, which are largely driven by chronic

inflammatory stress. Dietary supplementation is a valid strategy to reduce the risk and severity
of such disorders. Palmitoylethanolamide (PEA) is an endocannabinoid-like lipid mediator with
extensively documented anti-inflammatory, analgesic, antimicrobial, immunomodulatory and neuro protective effects.

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